نتایج جستجو برای: T lymphocyte

تعداد نتایج: 729944  

Journal: :iranian journal of allergy, asthma and immunology 0
hajar vaseghi department of biology, faculty of biological sciences, gonbad kavous university, iran mohammad hossein sanati national  research center for genetic engineering and biotechnology, tehran, iran zohreh jadali skin and stem cell research center, tehran university of medical sciences, tehran, iran and department of immunology, school of public health, tehran university of medical sciences. tehran, iran

t cells have been identified as key players in the pathogenesis of type 1 diabetes. however, the exact role of t-cell subpopulations in this pathway is presently unknown. the purpose of this study was to assess the expression pattern of two lineage-specifying transcription factors gata - 3 and t - bet , which are important in t helper type 1 (th1) and th2 cell development , respectively. gene e...

Journal: :iranian journal of allergy, asthma and immunology 0
hajar vaseghi department of biology, faculty of biological sciences, gonbad kavous university, gonbad kavous, iran mohammad hossein sanati national  research center for genetic engineering and biotechnology, tehran, iran zohreh jadali skin and stem cell research center, tehran university of medical sciences, tehran, iran and department of immunology, school of public health, tehran university of medical sciences, tehran, iran

t cells have been identified as key players in the pathogenesis of type 1 diabetes. however, the exact role of t-cell subpopulations in this pathway is presently unknown. the purpose of this study was to assess the expression pattern of two lineage-specifying transcription factors gata - 3 and t - bet , which are important in t helper type 1 (th1) and th2 cell development , respectively. gene e...

Journal: :iranian biomedical journal 0
محمد علی شکرگزار mohammad ali shokrgozar حمید محمودزاده نیکنام hamid mahmoodzadeh-niknam فاضل شکری fazel shokri

unresponsiveness to hepatitis b surface antigen (hbsag) has been shown to be associated with dysfunction of the presenting cells (apc) and defect in the specific b-lymphocyte and/or t-lymphocyte repertoires.   direct determination of the frequency of specific t-lymphocytes together with complementary analysis of the naive circulating immune cells could provide valuable information about the cel...

A TABATABAIYAN, F TARABADI, M IZADYAR, T ZANDIEH,

The aim of this study was to evaluate the immune system and lymphocyte function in 41 Iranian β-thalassemic patients and 50 controls, ages ranging from 2 to 18 years. The patients consisted of 20 splenectomized and 21 non-splenectomized patients. They were treated with Desferal, and had received repeated blood transfusion. Laboratory investigations included measurement of total T lymphocyt...

Journal: :iranian biomedical journal 0
فرهاد ریاضی راد farhad riazi rad سهیلا اژدری soheila ajdary رامش عمرانی پور ramesh omranipour محمد حسین علیمحمدیان mohammad hossein alimohammadian زهیر ام حسن zahir hassan

background: cd4+ and cd8+ t cells are the main types of lymphocytes in cell-mediated immunity and play a central role in the induction of efficient immune responses against tumors. the frequencies of t cell subtypes in the peripheral blood and tumor tissues, and draining lymph nodes (dln) can be considered as useful markers for evaluation of the immune system in cancers. methods: in this study,...

Journal: :مجله بین المللی زیست و زیست پزشکی 0
gholam hossein ashrafi cancer study group, sec faculty, penrhyn road, kingston university london, kingston upon thames, uk, kt1 2ee dhaya perumal school of pharmacy and chemistry, sec faculty, penrhyn road, kingston university london, kingston upon thames, uk, kt1 2ee

few studies have been conducted on the causative factors associated with the development of cancer. infection by high risk human papillomaviruses (hpvs) have been implicated as causative agents in a variety of cancers. hpv is capable of evading immune system and establishing persistent infections. prolonged infection and lesion maintenance are associated with higher risk of neoplastic progressi...

Ali Ariafar Mohsen Sarkarian Nasrollah Erfani, Nazanin Nazari Saeed Abbasi-Sarvak Saeideh Sadat Shobeiri Shahryar Zeighami Zahra Faghih,

Background: Cytotoxic CD8+ T cells, as essential parts of the adaptive immune system, play pivotal roles in anti-tumor immune responses. It is well documented that cytokine expression profiles and activation status of these cells during anti-tumor immune responses affect the outcome of host-tumor interaction. Objective: To investigate the percentages of CD8+ lymphocytes and their subsets in...

Dariush Haghmorad Mahdieh Khazaee Mahmoud Mahmoudi Maryam Rastin Maryam Sahebari Mitra Masoudian Mohammadreza Hatef Nafiseh Tabasi Reza Nosratabadi Shahrzad Zamani

Objective(s):  Apoptosis is a tightly regulated process and plays a crucial role in autoimmune diseases. Because abnormalities in apoptosis are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), in present study we studied the apoptosis in T lymphocytes from Iranian SLE patientsat protein and gene expression levels for some molecules which are involved in apopt...

AA POURFATHOLLAH, AF SARRAF NEJAT, AR YALDA, MB ESLAMI,

Human brucellosis is a major health problem in developing countries. A number of patients with human brucellosis do not recover from the acute stage of the disease and pass into the chronic form. Since the pathophysiology of this change is not well understood, we studied the T-cell subsets during the acute, subacute and chronic forms of human brucellosis. In this study we found alterations...

Journal: :journal of medical signals and sensors 0
mohamed bagher tavakoli ali kiani mahnaz roayaei

many cellular damages either in normal or cancerous tissues are the outcome of molecular events affected by ionizing radiation. t‑cells are the most important among immune system agents and are used for biological radiation dose measurement in recommended standard methods. the herbs with immune modulating properties may be useful to reduce the risk of the damages and subsequently the diseases. ...

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